Microsoft about to release a new update to fix 23 vulnerabilities on different MS products, this update going to fix several critical vulnerabilities in windows operating system, Internet Explorer, Silverlight and .NET framework.
According to the advance notification we find a patch to Microsoft Forefront UAG a security solution that delivers secure remote access to corporate resources for employees. Severity rating of this vulnerability is important but for hackers this can be more than important as a new exploit can lead to breach the total remote system and execute remote software.
Most of patches require system restart but before you apply updates you need to test them to avoid any software issue, so try to have the update on similar system and if there is no software conflicts with your application apply them on your network.
You can find more information on Microsoft Security Bulletin Advance Notification for October 2011.